The Comparison of Susceptibility to SARS-CoV-2 Infection between Pediatric and Adults

Authors

  • Haniye Shafipour Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Milad Zandi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Mona Fani Department of Pathobiology and Laboratory Sciences, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
  • Saber Soltani Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Samaneh Abbasi Department of Microbiology, Faculty of Medicine, Abadan University of Medical Sciences, Abadan, Iran
Abstract:

SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and is responsible for the recent pandemic in the world. It has been recently recognized as a challenge for public health and a significant cause of severe illness in all age groups. Young children and older people are susceptible to SARS-CoV-2 infection. However, children usually present mild symptoms compared to adult patients. The relationship between age, severity, and COVID-19 transmission is compared to determine whether there is any reasonable relationship between age and COVID-19. It should be mentioned that some risk factors may increase the probability of developing severe COVID-19 by advancing age, such as pathophysiological changes in the respiratory system, angiotensin-converting enzyme 2 expression in the nasopharynx, and smoking. Susceptibility to SARS-CoV-2 infection is independent of age, but the mortality rate of COVID-19 depends on age.

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Journal title

volume 8  issue 4

pages  241- 246

publication date 2021-11

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